The four best cities to launch a startup in Latin America

Winter is on the way and perhaps you’re thinking about moving south. Whether you’re looking to Latin America for new markets, hoping for cheaper rent or running from shoveling, the southern half of the Americas have a few promising hubs full of new accelerators, incubators, and increasingly, success stories.

Although it’s highly segmented on national and economic lines, the Latin market represents the second-most spoken language in the world (Spanish), and opportunities there are increasing as technology reaches the masses. Here’s a flyover of the most promising startup hubs south of the Rio Grande. These four urban hubs represent some of the most promising regions in Latin America — with growing talent pools, universities, government support and growing appreciation for innovative business models.

Buenos Aires, Argentina

Arguably the most cosmopolitan city in South America, Buenos Aires may also be the region’s largest startup hub. While the economic stories out of Argentina are all about the national credit default, some of South America’s largest successes — like MercadoLibre, one of the only Latin American startups now traded on NASDAQ — have come out of Argentina. Bitpagos just announced $600,000 in seed funding to make Bitcoin more usable in South America.

On the other hand, Wisconsin entrepreneur-turned-investor Nathan Lustig warns that the investors in the “Paris of South America” also face red tape and economic instability.

“If you’re trying to start a business, Argentina, along with Venezuela, would be the last place I would start,” Lustig said. “From an entrepreneur’s side, I wouldn’t touch Argentina … because of all of the headaches, even though it’s an amazing market with highly educated people, a cosmopolitan city.”

Drawbacks: Challenge of navigating a parallel economy; nearly impossible to exchange large dollar amounts.

Comparable startup community size: Boulder, Colorado. Buenos Aires has fewer investors than Boulder, but a similar number (330) of startups, according to And both cities offer some nice scenery. Expect a more business-friendly business culture in the Rockies than east of the Andes, however.

São Paulo, Brazil

You can’t tour Latin America without giving credit to the biggest kid on the block.

Brazil’s largest city, São Paulo, has a GDP larger than the GDPs of neighboring Argentina, Chile, Uruguay, Bolivia and Paraguay combined, according to fnbox. The 22 incubators in the city have already pumped out 182 companies. Successes include Boo Box for online advertising and Peixe Urbano for shopping.

Lustig pointed out that Brazil’s language, culture and size call for recognition as its own market in Latin America. “It’s probably worth thinking about Brazil as almost a separate thing,” he said.

Drawbacks: Programs like Start-Up Brasil offer more red tape than comparable initiatives in neighboring countries. Markets differ widely in the poorer north of Brazil compared to the more developed south. How’s your Portuguese?

Comparable startup community size: Cambridge, MA. I’m not comparing cultures here, but São Paolo and Cambridge have matching average valuations and number of startups. 

Santiago, Chile

Chile’s government brought new attention to the Andean nation when it started handing out $40,000 each to up to 300 startup teams in 2010 through an accelerator program dubbed Start-Up Chile. The program was among the first of its kind worldwide.

In the midst of Latin America’s undeniable machismo, the capital of female entrepreneurs is here in Santiago, where 20 percent of startup employees are women.

Chile has its share of successes like Cumplo, for peer-to-peer lending, or Compara Online, a unique site for comparing financial services, which has raised over $16 million to expand out of Chile.

Drawbacks: Start-Up Chile isn’t for everyone, and the program is the main reason you should be thinking of working on a global startup in Santiago of all places.

Comparable startup community size: Houston, Texas.

The sun rises on El Poblado, an upscale neighborhood on the mountainside surrounding Medellín, Colombia. Photo by Jamie Stark.

The sun rises on El Poblado, an upscale neighborhood on the mountainside surrounding Medellín, Colombia. Photo by Jamie Stark.

Medellín, Colombia

I know, Pablo Escobar. But Colombia is starting to change. Colombia’s second largest city was named 2013’s Innovative City of the Year by the Wall Street Journal magazine and Citibank. New startup infrastructure like the Ruta N incubator has attracted founders and potential employees from across the globe – like Dutchman Alexander Tegelaars, who was in Medellín working as a bartender and interviewing at the numerous startups popping up. He had an obvious affinity for the entrepreneurial spirit reviving Medellín. “It’s a cultural factor, the paisas,” Tegelaars said, using the Spanish word for countrymen used to describe those from Medellín.

Colombia’s famous startup sons, like Alexander Torrenegra and Andres Barreto, are pushing Colombia onto the world stage. The government is supportive of the tech community with initiatives like Ruta N has fostered the growth of such companies as Ideatech, which makes nanosatellites that can reportedly be launched into space for a few thousand dollars.

Drawbacks: I was robbed at knifepoint steps from Ruta N incubator. Although the crime rate has fallen here, the city remains in the top 30 most dangerous cities in the world. Medellín, like any city grappling with intense wealth inequality and past violence, has some work to do.

Comparable startup community size: Milwaukee, Wisconsin.

These and similar urban hubs in Latin America need both time and progress to rival first tier startup communities in the U.S. or Europe. Talent here must adjust to the idea of equity rather than an immediate corporate paycheck; more money beyond seed funding is needed to carry worthy businesses higher, and innovation must be promoted more than mere copycatting (“The Uber of Colombia”) to earn the moniker “innovative” for these LatAm hubs.

Jamie Stark is a freelance journalist covering startup culture and social entrepreneurship in sunny Latin America. Follow him on Twitter @JamieStark.